PimCell™

Welcome to our latest blog post where we delve into the fascinating world of biomedical research, specifically focusing on the in vitro blood-brain barrier (BBB) models. Today, we’re exploring why having a straight and well-defined structure is crucial for these models. Whether you’re a student, researcher, or simply a science enthusiast, this post will shed light on the importance of structural integrity in scientific research.

In the realm of biomedical research, brain organoids have emerged as an avant-garde tool, enabling scientists to delve deeper into the intricacies of human brain development and diseases. These miniaturized, simplified versions of the brain, grown from stem cells, offer a dynamic model to study a range of neurological conditions. However, a persistent challenge in the cultivation of brain organoids is the formation of a necrotic core — a problem that is intricately linked to the absence of vascularization within these tissue structures. This blog will unpack the issue of the necrotic core and the groundbreaking efforts towards achieving in vitro vascularization to mitigate this challenge.

Microscopy is an invaluable tool in the world of science, allowing us to peer into the hidden realms of the microscopic world. When it comes to microscopy, the choice of equipment can greatly impact the quality of your research. One critical decision is whether to use glass bottom dishes or glass bottom plates. In this blog, we'll explore why glass bottom dishes are often considered the superior choice for microscopy applications.